Ketamine and Psychosis


While ketamine works very well in bipolar patients, those with psychotic features must maintain their antipsychotic while undergoing ketamine therapy.

Ketamine does nothing to solve psychosis and mania, so use a mood stabilizer such as lamictal, and an antipsychotic such as risperidone, along with a stimulant and sleep medication if those are part of your routine.

Ketamine does not solve ADD/ADHD and mania or cure wake and sleep issues.

Note lamictal and risperidone have been shown to lower the effectiveness of ketamine. See the contraindications page for more information.


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